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Anti-CD19 CAR-T Cells

保存条件:-80°C(dryice)保质期:Cellsareshippedindryiceandshouldimmediatelybethawedorstoredinliquidnitrogenuponreceipt

产品型号:

更新时间:2024-11-22

  • 详细介绍
  • 品牌BPS Bioscience
  • 保存条件:

    -80°C (dry ice)

  • 保质期:

    Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.

  • 英文名:

    Anti-CD19 CAR-T Cells

  • 数量:

    1

  • 供应商:

    BPS Bioscience Inc.

  • CAS号:

    /

  • 规格:

    1 vial

The anti-CD19 CAR-T cells are produced by high-titer lentiviral transduction of human primary CD4+CD8+ T cells using the anti-CD19 CAR Lentivirus (CD19 ScFv-CD8-4-1BB-CD3ζ; SIN Vector, BPS Bioscience, #78601). These ready-to use CAR-T cells express an anti-CD19 CAR consisting the ScFv of CD19 (clone FMC63) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains. These CAR-T cells have been validated using flow cytometry (to determine the CAR expression) and co-culture cytotoxicity assays.
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