- 保存条件:
Room temp. (continental US) or gel packs
- 保质期:
Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
- 英文名:
SGI-1776 free base
- 数量:
1
- 供应商:
BPS Bioscience Inc.
- CAS号:
/
- 规格:
5 mg
SGI-1776 is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival. Through extensive biomedical characterization, SGI-1776 exhibits specificity to the three isoforms of the Pim family, including Pim-1, Pim-2, and Pim-3. Treatment with SGI-1776 induces apoptosis in CLL primary cell line.