- 保存条件：
gel packs
- 英文名：
b-AP15 (NSC-687852)
- 数量：
1
- 供应商：
BPS Bioscience Inc.
- CAS号：
/
- 规格：
5 mg
Blocks 26S proteasome activity by inhibiting the ubiquitin C-terminal hydrolase 5 (UCHL5) and ubiquitin-specific peptidase 14 (USP14) activities of the 19S regulatory subunit without affecting the catalytic activity of the 20S core subunit. b-AP15 displays several differences to bortezomib including insensitivity to over-expression of the anti-apoptotic mediator Bcl-2 and anti-tumor activity in four solid tumor models.
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