AAV5 Luciferase-eGFP

保存条件:-80°C(dryice)保质期:3-18month英文名:AAV5Luciferase-eGFP数量:1供应商:BPSBioscienceInc

产品型号:

更新时间:2024-11-23

  • 详细介绍
  • 品牌BPS Bioscience
  • 保存条件:

    -80°C (dry ice)

  • 保质期:

    3-18 month

  • 英文名:

    AAV5 Luciferase-eGFP

  • 数量:

    1

  • 供应商:

    BPS Bioscience Inc.

  • CAS号:

    /

  • 规格:

    50 µl x 2

Adeno-Associated Virus Serotype 5 (AAV5) differs from other parvovirus serotypes according to serological and DNA hybridization data, and AAV5 also uses different inverted terminal repeats (ITRs) compared to other AAV serotypes. AAV5 is the most efficient vector for transducing sensory neurons and is good at mediating gene transfer into human and murine airway epithelia. In addition, AAV5 vectors show a higher tropism for both mouse and human dendritic cells than AAV1, AAV2, AAV7, or AAV8.These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and enhanced Green Fluorescent Protein (eGFP) genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and eGFP as two separate proteins.
温馨提示:不可用于临床治疗。

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