产品分类

Product category

首页>产品中心>>细胞库 / 细胞培养>IL-15 Responsive Luciferase Reporter Cell Line

IL-15 Responsive Luciferase Reporter Cell Line

产品型号:

更新时间:2024-11-24

  • 详细介绍
  • 品牌BPS Bioscience
  • 数量:

    1

  • 供应商:

    BPS Bioscience

  • 细胞类型:

    稳转细胞系

  • 品系:

    Jurkat

  • 组织来源:

    /

  • 相关疾病:

    多种

  • 物种来源:

    human

  • 免疫类型:

    多种

  • 器官来源:

  • 运输方式:

    干冰

  • 年限:

    10

  • 生长状态:

    良好

  • CAS号:

  • 英文名:

    IL-15 Responsive Luciferase Reporter Cell Line

  • 注册证号:

    /

  • 规格:

    2管

This recombinant Jurkat cell line is a biologically relevant system to measure activation of the IL-15 cytokine receptor by IL-15. The cells were engineered for constitutive expression of human CD122 (IL-15Rβ; IL-2Rβ; NM_000878.4), and conditional expression of firefly luciferase driven by STAT5 response elements located upstream of the minimal TATA promoter. Expression of CD122 allows formation of a functional IL-15 receptor at the surface of Jurkat cells, which naturally express high levels of CD132 (also known as IL-15 receptor subunit γc). Activation of the STAT5 signaling pathway in response to IL-15 or IL-15 analogs can be monitored by measuring luciferase activity.

留言框

  • 产品:

  • 您的单位:

  • 您的姓名:

  • 联系电话:

  • 常用邮箱:

  • 省份:

  • 详细地址:

  • 补充说明:

  • 验证码:

    请输入计算结果(填写阿拉伯数字),如:三加四=7
联系方式 二维码

服务热线

13829799985

关注公众号