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ABT-888 (Veliparib)

●Purchase●DescriptionABT-888(Veliparib)isapotentinhibitorofbothPARP-1andPARP-2

产品型号:27101

更新时间:2024-11-26

  • 详细介绍
  • 品牌BPS Bioscience
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Description

ABT-888 (Veliparib) is a potent inhibitor of both PARP-1 and PARP-2. In the MX-1 breast xenograft model (BRCA1 deletion and BRCA2 mutation), ABT-888 potentiated cisplatin, carboplatin, and cyclophosphamide, causing regression of established tumors, whereas with comparable doses of cytotoxic agents alone, only modest tumor inhibition was exhibited.

Synonyms
Veliparib

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