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Engineered CHO cell line stably expressing human C-terminus MUC16 (CA125) transcript variant 4, from amino acid 13785 to 14507 (NM_024690.2). This portion of MUC16 contains several of the extracellular SEA modules, the transmembrane domain, and the short cytoplasmic tail of the protein. Surface expression of MUC16 was confirmed by flow cytometry. This stable clonal cell line was selected based on its high level of MUC16 expression compared to the parental CHO-K1 cell line.
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