STAT5 Luciferase Reporter Ba/F3 Cell Line

The STAT5 (Signal Transducer and Activator of Transcription 5) Luciferase Reporter murine Ba/F3 cell line monitors STAT5-mediated signal transduction pathways. It contains a firefly luciferase gene driven by STAT5 response elements located upstream of a minimal TATA promoter. After activation by relevant cytokines or growth factors, endogenous STAT5 binds to the response elements, inducing transcription of the luciferase reporter gene.

This cell line responds to mouse interleukin-3 (IL-3).

Figure 1: Illustration of STAT5 Luciferase Reporter Ba/F3 Cell Line.
Created with BioRender.com

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.