NF-κB Luciferase Reporter Raw 264.7 Cell Line

NF-κB Luciferase Reporter Raw 264.7 Cell Line is a Raw 264.7 cell line expressing firefly luciferase driven by four copies of the NF-kB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. This cell line has been functionally validated and responds to TNFα and RANKL

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