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MDM2 TR-FRET Assay Kit

●Purchase●DescriptionHumanMousedoubleminute2homolog (MDM2)isanE3ubiquitin-proteinligasethatfunctionsasanegativeregulatorofT-cellactivation

产品型号:79773

更新时间:2024-11-28

  • 详细介绍
  • 品牌BPS Bioscience
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Description

Human Mouse double minute 2 homolog (MDM2) is an E3 ubiquitin-protein ligase that functions as a negative regulator of T-cell activation. It is a potential drug target in cancer immunotherapy. It utilizes biotin-labeled ubiquitin and a terbium-labeled anti-GST antibody to complete the TR-FRET pairing. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications.

Synonyms
Mdm2,mouse double minute 2, human homolog, Hdm2

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