KRAS (G12C), Isoform A, His-Tag, GppNHp-Loaded Recombinant

●Purchase●DescriptionRecombinanthumanKRAS(GTPase),isoforma,encompassingaminoacids2-186(end)

产品型号：100641

更新时间：2024-11-28

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品牌	BPS Bioscience

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Description

Recombinant human KRAS (GTPase), isoform a, encompassing amino acids 2-186 (end). In this construct the N-terminal end of the protein contains a His-tag (6xHis) followed by an optimal TEV protease target sequence that allows cleavage of the His-tag from the protein (TEV: tobacco etch virus cysteine protease #50308). The protein also contains cancer-associated mutation G12C. The protein was affinity purified and loaded with GppNHp, a non-hydrolyzable GTP analog. Unbound GppNHp was removed by spin column. Ready for use in KRAS-RAF binding studies or inhibitor assays.

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Synonyms

C-K-RAS, CFC2, K-ras, kRas(G12C), kRas, KRAS proto-oncogene, GTPase, Kirsten Rat Sarcoma virus, NS, NS3, OES, RALD, KRAS1, KRAS2, RASK2, KI-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, c-Ki-ras, c-Ki-ras2

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