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Complex of human PI3 kinase (phosphatidylinositol-4,5-bisphosphate 3-kinase) catalytic subunit p110δ (also known as PIK3CD) and regulatory subunit p85α (also known as PIK3R1).
Recombinant human p110δ, encompassing amino acids 1-1044 (end), contains an N-terminal GST-tag. Recombinant human p85α, full length encompassing amino acids 1-724 (end), does not contain a tag. The proteins were co-expressed in Sf9 insect cells and formed a complex which was affinity purified.
PIK3R1, Phosphoinositide-3-Kinase Regulatory Subunit 1 (Alpha), GRB1, p85alpha