Tubastatin A hydrochloride

●Purchase●DescriptionTubastatinAisapotentHDAC6inhibitor

产品型号：27108

更新时间：2024-11-25

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品牌	BPS Bioscience

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Description

Tubastatin A is a potent HDAC6 inhibitor. It demonstrates over 1,000-fold selectivity against all other HDAC isoforms (IC50 >16 µM), excluding HDAC8 (IC50 = 0.9 µM). Tubastatin A induces a-tubulin hyperacetylation at 2.5 µM in primary cortical neuron cultures. In a model of oxidative stress induced by glutathione depletion, it displays dose-dependent neuronal protection of primary cortical neuron cultures at 5-10 µM.

This product has been cited 2 times.

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