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BAY-11-7082

●Purchase●DescriptionBAY-11-7082isaselectiveandirreversibleinhibitorofNF-BactivationbyblockingTNF--inducedphosphorylationofIB-withoutaffectingconstitutiveIB-phosphorylation

产品型号:27229

更新时间:2024-11-30

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BAY-11-7082 is a selective and irreversible inhibitor of NF-κB activation by blocking TNF-α-induced phosphorylation of IκB-α without affecting constitutive IκB-α phosphorylation. It also inhibits the TNF-α-induced surface expression of adhesion molecules ICAM-1, VCAM-1, and E-selectin in human endothelial cells.

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